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Benedict Monteiro
Education
MSc Genomic Medicine
King’s Collge/St George’s, University of London
London, UK
2021 - 2020
- Final grade: Distinction (82% overall average)
- Awarded academic scholarship at admission.
- Taught modules covered the generation, analysis and applications of omic data in clinical and research contexts.
- Research project thesis: “Preliminary liquid biopsy analysis of pancreatic ductal adenocarcinoma patients treated with immunotherapy” (76%)
BSc Biochemistry with French for Science
Imperial College London
London, UK
2020 - 2016
- Final grade: First Class Honours (71% overall average)
- Final year research project dissertation: “Environmental stress provokes a transcriptomic call to arms in Legionella pneumophila” (80%)
- Advanced final year modules: Bioinformatics (69%), Mechanisms of Gene Expression (70%), Damage & Repair in Biological Systems (72%)
- Cultural dissertation in French: “The importance of the Second Empire for the city of Paris” (74%)
Research Experience
Postgraduate Researcher
Vigilante Lab, CSCRM
King’s College London
2021 - 2021
- Developed a bioinformatic pipeline to analyse circulating tumour DNA from pancreatic ductal adenocarcinoma for markers predictive of immunotherapy response.
Undergraduate Researcher
Costa Lab, CMBI
Imperial College London
2020 - 2020
- Analysed RNA-Seq differential expression data to outline the transcriptomic response of the bacteria L. pneumophila to stressors.
Erasmus Research Placement
Zucman-Rossi Lab, CRC
Université de Paris, France
2019 - 2018
- Worked independently on a bioinformatic analysis of mutational signatures in liver cancer whole genome sequencing data.
- Performed all analyses and designed the results figure for the “mutational signatures” section in a genomic study of a rare type of paediatric liver cancer.
- Updated and maintain the R package Palimpsest with functions for the extraction and further study of new types of mutational signatures.
Teaching Experience
Graduate Teaching Assistant
Department of Life Sciences
Imperial College London
2021 - 2020
- Teaching core maths skills to Biology & Biochemistry undergraduates.
Publications
Integrated genomic analysis identifies driver genes and cisplatin-resistant progenitor phenotype in pediatric liver cancer
Cancer Discovery
N/A
2021
- Hirsch TZ, Pilet J, Morcrette G, Roehrig A, Monteiro BJ, Molina L, Bayard Q, Trepo E, Meunier L, Caruso S, Renault V, Deleuze JF, Fresneau B, Chardot C, Gonzales E, Jacquemin E, Guerin F, Fabre M, Aerts I, Taque S, Laithier V, Branchereau S, Guettier C, Brugieres L, Rebouissou S, Letouze E, Zucman-Rossi J. Integrated genomic analysis identifies driver genes and cisplatin-resistant progenitor phenotype in pediatric liver cancer. Cancer Discov. 2021 Apr 23:candisc.1809.2020. doi: 10.1158/2159-8290.CD-20-1809. Epub ahead of print. PMID: 33893148.